What is Syfovre and how does it help?

Dry Macular Degeneration, Retinal Tear, Tampa RetinaFebruary 26, 2025

What is Syfovre and how does it help?

Syfovre is a medication administered as an eye injection that has been FDA approved since 2023 for geographic atrophy, the advanced stage of dry age-related macular degeneration.
Syfovre targets a part of your immune system called the complement system that is overactive in patients with dry age-related macular degeneration.
The overactive complement system plays a role in attacking your healthy retina cells in your macula, slowly killing those cells and reducing central vision.
Syfovre specifically blocks the protein C3 in the complement system, slowing down the process of retina cell loss and central vision loss.
In clinical trial studies, Syfovre injections given in the eye every 1-2 months slowed down the loss of retina cells (geographic atrophy) by around 20% at 2 years and 30% at 3 years.

Ask your retina doctor about the risks, benefits and alternatives to receiving syfovre injections and if you are a candidate to receive the medication.

The doctors at Retina Associates of Florida provide the latest diagnostic and treatments for age-related macular degeneration (AMD) in their Tampa, Brandon and Lakeland offices.

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