Marc C. Peden, MD

Education:

  1. University of Florida College of Medicine Department of Ophthalmology:
    Vitreoretinal Surgery and Disease Fellowship

    Gainesville, Florida
    7/1/2007 to 6/30/2009
  2. University of Florida College of Medicine Department of Ophthalmology: Residency
    Gainesville, Florida
    7/1/2004 to 6/30/2007
  3. University of Florida College of Medicine Department of Internal Medicine: Internship
    Gainesville, Florida
    7/1/2003-6/30/2004
  4. University of Florida College of Medicine
    Gainesville, Florida
    M.D., Awarded May 24, 2003 with Academic Honors
  5. University of Florida
    Gainesville, Florida
    B.S. in Zoology with High Honors, minor in Business Administration, 1997

Academic Appointments:

  1. University of Florida Department of Ophthalmology
    Adjunct Assistant Professor 12/16/2011-current
    Gainesville, Florida
  2. University of Florida Department of Ophthalmology
    Assistant Professor 7/6/2009-12/16/2011
    Director of Vitreo-retinal Disease and Surgery Service 11/2010-12/16/2011
    Gainesville, Florida

Hospital Appointments:

  1. Memorial Hospital of Tampa
    Tampa, Florida
    12/13/2011-current
  2. Shands Hospital at the University of Florida
    Gainesville, Florida
    7/2003-12/2011

Licensure/Certification:

  1. American Board of Ophthalmology:
    Written Qualifying Exam, passed 3/2008
    Oral Qualifying Exam, passed 10/2008
  2. Florida Medical Board: issued 6/21/06, expires 1/31/12 License # ME96228

Professional Memberships:

  1. American Society of Retina Specialists 2009-current
  2. American Academy of Ophthalmology 2004-current
  3. Florida Society of Ophthalmology 2007-current
  4. American Medical Association 1999-2007
  5. Florida Medical Association 1999-current
  6. Alachua County Medical Society 2009- current

Research Experience:

  1. University of Florida Center for Vision Research: 2009-current
    1. Co-Principle Investigators:Dr. Marc Peden MD, and Dr. Mark Sherwood MD
      Project- AAV mediated gene delivery to the subretinal and suprachoroidal space via ab-externo approach using a 250 micron microcatheter
    2. Co-Principal Investigators: Dr Marc Peden MD and Dr. Tim Garrett PhD
      Project- Analysis of macular drusen in rhesus monkeys; an animal model of macular drusen
      Funding: Florida Lions Club
    3. Collaborator: NIH, R01 Grant, (1R01LM010813-01) (PI, 2nd PI: Cendan, Co-Is: Lind, Johnsen, Cuty-Ruiz) 2009-current.
      Project- Neurological Exams Teaching & Evaluation Using Virtual Patient.
  2. University of Florida Department of Ophthalmology, 2005-2006
    1. Faculty Advisor- Dr. Ramakrishna Ratnakaram MD, OD
      Project- The effect of intravitreal silicone oil on intraocular pressure following pars plana vitrectomy.
  3. University of Florida Center for Vision Research, March-June 2003
    1. Principle Investigator- Dr. Shalesh Kaushal, MD, PhD.
      Mentor- Dr. Adrian Timmers PhD
      Project- Rescue of retinal function and rhodopsin folding in a P23H rat model of retinitis pigmentosa using injected isomers of retinaldehyde as chaperones.
  4. University of Florida Center for Vision Research, 1996-1997
    1. Principle Investigator- Dr. Paul A. Hargrave PhD.
      Mentors- Dr. Clay Smith PhD.,& Dr. Mick Popp PhD.
      Project- Molecular aspects of arrestin- determining surface regions of arrestin that interact with photo-excited rhodopsin.
      Senior Thesis- "Neutralization of lysine 201 in bovine arrestin via oligonucleotide-directed mutagenesis, and its effects on binding specificity."- Received High Honors

Presentations

  1. Therapeutic Approaches to the Posterior Eye- A Clinical Perspective, Marc Peden, Center for Vision Research meeting -"Development and Delivery of Therapeutic Agents for the Eye." March 8-9, 2010, Gainesville, FL.
  2. Safety Study of Ab-Externo AAV Gene Transfer Delivery to the Subretinal and Suprachoroidal Space Using a 250 Micron Flexible Microcatheter, M. C. Peden, C. Meyers, Q. Li, R. Yamamoto, C. Roberts, J. Minn1, M. Levine, V. Chiodo, A. Lewin, W. Hauswirth, R. Ratnakaram, M. Sherwood, ARVO Annual Meeting May 3-May 7 2009, Fort Lauderdale, FL.
  3. Reduction of Macular Edema at One Hour Following Intravitreal Bevacizumab as Demonstrated by Serial OCTs, D.E. Welch, S. Adams, M. Peden, R. Ratnakaram, S. Kaushal, ARVO Annual Meeting April 27-May 1 2008, Fort Lauderdale, FL.
  4. An Alternative Technique for Implantation of Scleral-Fixated Intraocular Lens, M.C. Peden, S.G. Adams, Jr., B. Huffman, H. Adams, S. Kaushal, ARVO Annual Meeting April 27-May 1 2008, Fort Lauderdale, FL
  5. Disciform Scarring in Macular Degeneration Correlates With Loss of Retinal Nerve Fiber Layer Thickness on Optical Coherence Tomography (OCT), M.H. Oltmanns, M. Peden, S. Adams, R. Ratnakaram, S. Kaushal, ARVO Annual Meeting April 27-May 1 2008, Fort Lauderdale, FL.
  6. Wound Closure in Sutureless 23 Gauge Pars Plana Vitrectomy: Ubm, Slit Lamp Photography, and Iop Results, S.G. Adams, Jr., M. Peden, R. Ratnakaram, S. Kaushal, ARVO Annual Meeting April 27-May 1 2008, Fort Lauderdale, FL.
  7. Intravitreal Avastin vs Pegaptanib in treatment of choroidal neovascular membranes, R. Ratnakaram, M. Peden, S. Adams, ARVO Annual Meeting May 6-10, 2007, Fort Lauderdale, FL.
  8. Combination PDT and VEGF inhibitor therapy for exudative ARMD, S.G. Adams, M. Peden, R. Ratnakaram, ARVO Annual Meeting May 6-10, 2007, Fort Lauderdale, FL.
  9. Effect of silicone oil on intraocular pressure following pars plana vitrectomy, M.C. Peden, C.W. Sheets, S. Adams, H.D. Vaishnav, R. Ratnakaram, ARVO Annual Meeting, May 6-10, 2007, Fort Lauderdale, FL.

Publications

  1. Robert G. Steen, Anne E. Kwitek-Black, Christopher Glenn, Jo Gullings-Handley, William Van Etten, O. Scott Atkinson, Diane Appel, Simon Twigger, Melanie Muir, Tim Mull, Mary Granados, Mushira Kissebah, Kerri Russo, Robbin Crane, Michael Popp, Marc Peden, Tara Matise, Donna M.Brown, Jian Lu, Stephen Kingsmore, Peter J. Tonellato, Steve Rozen, Donna Slonim, Peter Young, Margit Knoblauch, Abraham Provoost, Detlev Ganten, Steven D. Colman, Jonathan Rothberg, Eric S.Lander, and Howard J. Jacob, A High Density Integrated Genetic and Radiation Hybrid Map of the Laboratory Rat, Genome Research 1999, May.
  2. Peden MC, Bhatti MT, Subperiosteal orbital hemorrhage complicating cardiac surgery, Cardiovasc Intervent Radiol. 2004 May-Jun;27(3):294-6.
  3. Matthew A Cunningham, Marc C Peden, Donald M. Downer, and Ramakrishna Ratnakaram, Bilateral retinochoroiditis in a case of acute primary toxoplasmosis in an immunocompetent patient, Digital Journal of Ophthalmology,2006 Vol 12, Num 2.
  4. Sheets C, Peden M, Guy J. Idiopathic intracranial hypertension in a transgender man. J Neuro-Ophthalmol. 2007:27:313-315
  5. Marc C Peden, Arvind Neelakantan,, Christine Orlando, Shahab A Khan, Alan Lessner, M. Tariq Bhatti. Breaking the mold of orbital cellulitis, Surv Ophthalmol. 2008 Nov-Dec;53(6):631-5
  6. Marc Peden, Serrhel Adams, Bryan Huffman, Shalesh Kaushal. An alternative technique for implantation of scleral-fixated intraocular lens, J Cataract Refract Surg. 2009 Feb;35(2):226-9
  7. Damon E. Welch, MD; Hany Elmariah; Marc C. Peden, MD; Serrhel G. Adams, MD, PhD; Ramakrishna Ratnakaram, MD, OD; Shalesh Kaushal, MD, PhD. Short-term Response of Macular Edema to Intravitreal Bevacizumab, Br J Ophthalmol. 2009 Apr 28. [Epub ahead of print]
  8. Robert M Knape, Marc C. Peden, The bitter taste of whiplash, Eyenet- AAO publication 2010 Jan: 41-43.
  9. M. C. Peden, J. Min,C. Meyers, Q. Li, R. Yamamoto, Z. Lukowski, M. Levine, W. Hauswirth, R. Ratnakaram, W. Dawson, W.C. Smith and M. B. Sherwood, Ab-Externo AAV Gene Transfer Delivery to the Suprachoroidal Space Using a 250 Micron Flexible Microcatheter. PLoS One. 2011 Feb 11;6(2):e17140.
  10. Bhardwaj N, Perez J, Peden M, Optic Neuropathy from Cobalt Toxicity in a Patient who Ingested Cattle Magnets, Neuro-Ophthalmology. Feb 2011;35(1): 24-26.
  11. Knape RM, Zavaleta EM, Clark CL 3rd, Khuddus N, Peden MC. Intravitreal bevacizumab treatment of bilateral peripapillary choroidal neovascularization from optic nerve head drusen, J AAPOS. 2011 Feb;15(1):87-90.
  12. Peden M , Chuah J, Kotranza A, Johnsen K, Lok B, Cendan J, NERVE- 2: A Three Dimensional Patient Simulation of Oculomotor Nerve Palsy. MedEdPORTAL; 2010. Available from: http://services.aamc.org/30/mededportal/servlet/s/segment/mededportal/?subid=8383
  13. Peden M , Chuah J, Kotranza A, Johnsen K, Lok B, Cendan J, NERVE- A Three Dimensional Patient Simulation for Evaluating Cranial Nerve Function. MedEdPORTAL; 2011. Available from: http://services.aamc.org/30/mededportal/servlet/s/segment/mededportal/?subid=8255
  14. Jacobson SG, Cideciyan AV, Ratnakaram R, Heon E, Schwartz SB, Roman AJ, Peden MC, Aleman TS, Boye SL, Sumaroka A, Conlon TJ, Calcedo R, Pang JJ, Erger KE, Olivares MB, Mullins CL, Swider M, Kaushal S, Feuer WJ, Iannaccone A, Fishman GA, Stone EM, Byrne BJ, Hauswirth WW, Gene Therapy for Leber Congenital Amaurosis Caused by RPE65 Mutations: Safety and Efficacy in 15 Children and Adults Followed Up to 3 Years, Arch Ophthalmol. 2011 Sep 12. [Epub ahead of print]
  15. Zavaleta EM, Knape RM, Pérez JA, Clark CL, Peden MC, Spectral Domain Optical Coherence Tomography in Bilateral Lightning Maculopathy Before and After Internal Limiting Membrane Peel, (in submission to Retinal Cases and Brief Reports)

Clinical Trials

  1. CO-INVESTIGATOR: (ongoing)

    • Phase I Trial of Gene Vector to Patients With Retinal Disease Due to RPE65 Mutations (LCA)
  2. PRINCIPLE INVESTIGATOR: (ongoing)
    • Genentech RISE Study: Protocol #FVF417G
  3. SUB-INVESTIGATOR: (closed)
    • Potentia POT4 Study: Protocol #POT-CP-1006
    • Ophthotech: Protocol # OPH2000

Honors and Awards

  1. University of Florida Department of Ophthalmology: Resident member of Residency Selection Committee, 2005-2006 and 2006-2007.
  2. Florida Society of Ophthalmology: Florida Resident Delegate to Academy of Ophthalmology Mid-year forum, April 2007
  3. University of Florida College of Medicine:
    • Gold Humanism Honor Society, Chapman Chapter, 2003-current – Inaugural inductee
    • Alpha Omega Alpha Honor Medical Society, 2002-current Junior inductee
  4. University of Florida: BS in Zoology awarded with High Honors

Volunteer/Service

    1. University of Florida College of Medicine
      • University of Florida College of MedicineMedical College Council, 2000-2003 -Position held- Secretary, 2001-2002, President 2002-2003
      • University of Florida College of Medicine Equal Access Clinic, 1999-2003 -Positions held- Secretary, 1999-2000, Co-Director, 2000-2001
      • Alachua County Crisis Center, 1997-1999 – Phone counselor
      • Nicaraguan Medical Mission, June 1997, 1998, 1999, 2000, 2011

Interests/Hobbies

  1. Queen of Peace Catholic Church
  2. Private Pilot- Certificate obtained Jun 2000- April 2002
  3. Fishing, Boating, Tennis, Gardening, Spending time with family

Employment

  1. Retina Associates of Florida, P.A., 2012-current
  2. University of Florida
    1. Assistant Adjunct Professor
    2. Assistant Professor Department of Ophthalmology 2009-2011
  3. Veterans Administration Hospital
    1. Fee basis ophthalmic technician 2005-2006
    2. Fee basis physician 2006- 2009
  4. CuraGen Corporation, September 1997 – January 2000
    1. Research Associate II- Supervisor of sequencing data analysis, Lab Manager of Gene mapping facility
    2. Awards- Employee of the month, October 1997